www.woman-health.org Homepage Women's Health Gynecology Obstetrics Medline Women's health Guide
default
Search
February 5, 2012
Table of Contents

1 Introduction
5 Role
Decidua

Wikipedia

 

Decidua is the term for the uterus|uterine lining (endometrium) during a pregnancy. It is formed under the influence of progesterone and serves to support and interact with the gestation. The decidua represents the maternal portion of the placenta.




The word comes from the Latin deciduus, meaning falling off or shedding.





After ovulation, in mammals, the endometrial lining becomes transformed into a secretory lining in preparation to accept the embryo. Without implantation the secretory lining will be absorbed (estrous cycle) or shed (menstrual cycle). With implantation the lining now termed decidua evolves further during the pregnancy. The decidua is shed during the parturition process.




Different layers of the deciduas have been described, a compact outer layer (stratum compactum), an intermediate layer (stratum spongiosum), and a boundary layer adjacent to the myometrium. That part of the deciduas that interacts with the trophoblast is the decidua vera (???true decidua???), the remainder of the decidua is termed the decidua parietalis. The decidua has a histology|histologically distinct appearance displaying large polygonal decidua cells in the stroma. Vascularity is enhanced. Its leukocyte population is distinct with the presence of large endometrial granular leukocytes being predominant, while polynuclear leukocytes and B-cells are scant. The border to the trophoblast is called Nitabuch???s layer.




As the maternal interface to the embryo the decidua participates in the exchanges of nutrition, gas, and waste with the gestation. It also protects the pregnancy from the maternal immune system. Further, the decidua has to allow a very controlled invasion of the trophoblast.




The decidua secretes hormones, growth factors, and cytokines. It has receptors for estrogen, progesterone, growth hormone, and others. Among its products are hormones commonly associated with other organs such as cortisol, CRF, GnRH, prolactin, and relaxin. Decidual prolactin is not under dopaminergic control. Pregnancy protein 14 (PP-14) appears to be a specific product of the secretory and decidual lining. Other factors released include interleukin-15, vascular endothelial growth factor (VEGF), and insulin-like growth factor binding proteins. A reasonable understanding of the role and interplay of these hormones and factors has not been evolved.





  • In case of an extrauterine pregnancy, the endometrium nevertheless becomes decidualized. A women may shed the lining in the form of a decidual cast which may be mistaken as a miscarriage, when, in fact, the ectopic still persists.

  • A decidual reaction can be observed in tissue of the peritoneum and ovary during a pregnancy and represents a response of stromal tissue to progesterone.






#http://www-medlib.med.utah.edu/WebPath/PLACHTML/PLAC094.html Histologic picture
#http://education.yahoo.com/reference/gray/subjects/subject?id=12 Gray???s anatomy

Category:Anatomy
Category:Obstetrics


This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Decidua".


Last Modified:   2005-12-23


Search
All informatin on the site is © www.woman-health.org 2002-2011. Last revised: January 2, 2011
Are you interested in our site or/and want to use our information? please read how to contact us and our copyrights.
To let us provide you with high quality information, you can help us by making a more or less donation: