Femarelle (DT56a) is as a selective estrogen receptor modulator (SERM) for the treatment of menopause and bone health. DT56a is a standardized compound derived from soybean.

In animal models, Femarelle exerts agonistic (stimulatory) activity on estrogen receptors in the brain and bone. The compound has been reported to alleviate menopausal symptoms such as hot flushes and elevate bone mineral density (BMD), while having no proliferative effects on isolated breast cancer cell lines and uterine tissues of rats.

Femarelle was found to regenerate the bone through increased osteoblast activity, which makes it a possible agent for postmenopausal bone loss.

Although stimulating estrogen receptors, Femarelle does not appear to change the hormonal blood profile . A recent study found that Femarelle has no effect on clotting in both healthy and thrombophilic women.

Femarelle (Finland, Greece, Italy, Spain, Israel, USA, India, Latvia, Lithuania, Estonia)

Tofupill (Norway, Sweden, Cyprus, Mexico)