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February 11, 2012 |
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Gestational choriocarcinoma is a malignant trophoblastic tumour arising from any gestational event during pregnancy in the reproductive female. Women with gestational choriocarcinoma may present with abnormal vaginal bleeding, persistent markedly elevated human chorionic gonadotropin|βhCG, or a history of prior pregnancy. Most patients develop gestational choriocarcinoma shortly after gestational anomalies, but pathology may occur after a long latency of years. Grossly, a red hemorrhage|hemorrhagic mass is seen in the uterus, though it may vary in size. Often, diagnosis is presumptive, and based on clinical findings and the identification of a malignant trophoblast. At the time of diagnosis, more than 90% of patients already have lung metastases, though there are also less frequent metasteses to the brain and liver. With chemotherapy, there is an 80% 5-year survival rate. Ultimately, death is related to liver and brain metastases. med-stub Category:Oncology Category:Obstetrics This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Gestational choriocarcinoma".
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